| Item Type | Name |
|
Concept
|
Acute Disease
|
|
Concept
|
Antigens, Neoplasm
|
|
Concept
|
Antigens, Ly
|
|
Concept
|
Alkylation
|
|
Concept
|
Breast Neoplasms
|
|
Concept
|
Antigens, Differentiation
|
|
Concept
|
Antineoplastic Agents
|
|
Concept
|
Animals
|
|
Concept
|
Base Sequence
|
|
Concept
|
Azacitidine
|
|
Concept
|
Autoantibodies
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Chromosomes, Human, Pair 5
|
|
Concept
|
Chromosomes, Human, Pair 7
|
|
Concept
|
Death, Sudden
|
|
Concept
|
Interleukin-2
|
|
Concept
|
Leukemia, Erythroblastic, Acute
|
|
Concept
|
Database Management Systems
|
|
Concept
|
Child, Preschool
|
|
Concept
|
Glycoproteins
|
|
Concept
|
Cytarabine
|
|
Concept
|
Drosophila melanogaster
|
|
Concept
|
Melanoma, Experimental
|
|
Concept
|
Killer Cells, Natural
|
|
Concept
|
Graft Rejection
|
|
Concept
|
T-Lymphocytes, Helper-Inducer
|
|
Concept
|
Immune Tolerance
|
|
Concept
|
Herpesvirus 4, Human
|
|
Concept
|
Inflammation
|
|
Concept
|
Isoantibodies
|
|
Concept
|
Genes, MHC Class I
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Laryngeal Edema
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Mitoxantrone
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Herpes Simplex
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Major Histocompatibility Complex
|
|
Concept
|
Receptors, Antigen
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Risk Factors
|
|
Concept
|
Receptors, Immunologic
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
RNA, Viral
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Genes, ras
|
|
Concept
|
RNA
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Humans
|
|
Concept
|
Immunization
|
|
Concept
|
Bone Marrow Transplantation
|
|
Concept
|
Germ-Line Mutation
|
|
Concept
|
CD28 Antigens
|
|
Concept
|
Histocompatibility Antigens Class I
|
|
Concept
|
Leukemia, Myeloid
|
|
Concept
|
Lymphoid Tissue
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
Benchmarking
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Tyrosine
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Cell Adhesion Molecules
|
|
Concept
|
Genes, Tumor Suppressor
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Leukemia, Myeloid, Acute
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Chromosomes, Mammalian
|
|
Concept
|
Mouth Neoplasms
|
|
Concept
|
Consensus Sequence
|
|
Concept
|
Self Tolerance
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
CD8-Positive T-Lymphocytes
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Antigens, CD34
|
|
Concept
|
Evolution, Molecular
|
|
Concept
|
Antineoplastic Agents, Alkylating
|
|
Concept
|
MAP Kinase Kinase Kinases
|
|
Concept
|
Calcineurin
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Immunoconjugates
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Fatal Outcome
|
|
Concept
|
NIH 3T3 Cells
|
|
Concept
|
Internet
|
|
Concept
|
3' Untranslated Regions
|
|
Concept
|
CD40 Ligand
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Early Growth Response Protein 1
|
|
Concept
|
Interleukin Receptor Common gamma Subunit
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Sulfonamides
|
|
Concept
|
Ubiquitin-Protein Ligases
|
|
Concept
|
Proto-Oncogene Proteins c-cbl
|
|
Concept
|
CTLA-4 Antigen
|
|
Concept
|
Sialic Acids
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Autoimmunity
|
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily K
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Heart Transplantation
|
|
Concept
|
DNA Copy Number Variations
|
|
Concept
|
CD4-CD8 Ratio
|
|
Concept
|
Limit of Detection
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Gene Expression Regulation, Leukemic
|
|
Concept
|
Lymphocyte Subsets
|
|
Concept
|
Genes, p53
|
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
|
Concept
|
CD2 Antigens
|
|
Concept
|
Cellular Senescence
|
|
Concept
|
HL-60 Cells
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Myeloid Progenitor Cells
|
|
Concept
|
Receptors, Natural Killer Cell
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
K562 Cells
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Hep G2 Cells
|
|
Concept
|
Pathology, Molecular
|
|
Concept
|
Haploinsufficiency
|
|
Concept
|
Acute Chest Syndrome
|
|
Concept
|
Anemia, Sickle Cell
|
|
Concept
|
Chromosome Aberrations
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Ethylnitrosourea
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Hemagglutinins
|
|
Concept
|
Immunity, Innate
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Immunologic Memory
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Translocation, Genetic
|
|
Concept
|
Mutagenesis, Insertional
|
|
Concept
|
Mice, SCID
|
|
Concept
|
Mice, Inbred NOD
|
|
Concept
|
Clonal Anergy
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
U937 Cells
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Academic Article
|
2B4 (CD244)-CD48 interactions provide a novel MHC class I-independent system for NK-cell self-tolerance in mice.
|
|
Academic Article
|
Role of natural killer cell subsets in cardiac allograft rejection.
|
|
Academic Article
|
2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells.
|
|
Academic Article
|
2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells.
|
|
Academic Article
|
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
|
|
Academic Article
|
Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
|
|
Academic Article
|
The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
|
|
Academic Article
|
Widespread genetic epistasis among cancer genes.
|
|
Academic Article
|
Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
|
|
Academic Article
|
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
|
|
Academic Article
|
Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays.
|
|
Academic Article
|
The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
|
|
Academic Article
|
Therapy-related myeloid neoplasms: when genetics and environment collide.
|
|
Academic Article
|
System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.
|
|
Academic Article
|
A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
|
|
Academic Article
|
Cytotoxic Therapy-Induced Effects on Both Hematopoietic and Marrow Stromal Cells Promotes Therapy-Related Myeloid Neoplasms.
|
|
Academic Article
|
CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions.
|
|
Academic Article
|
The significance of CUX1 and chromosome 7 in myeloid malignancies.
|
|
Academic Article
|
Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms.
|
|
Academic Article
|
EGR1 Haploinsufficiency Confers a Fitness Advantage to Hematopoietic Stem Cells Following Chemotherapy.
|
|
Academic Article
|
Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells.
|
|
Concept
|
Radiation Exposure
|
|
Concept
|
Abatacept
|
|
Concept
|
Signaling Lymphocytic Activation Molecule Family
|
|
Concept
|
Signaling Lymphocytic Activation Molecule Family Member 1
|
|
Concept
|
CD48 Antigen
|
|
Concept
|
Gene Editing
|
|
Concept
|
Clustered Regularly Interspaced Short Palindromic Repeats
|
|
Concept
|
Carcinogenesis
|
|
Concept
|
Triple Negative Breast Neoplasms
|
|
Concept
|
Datasets as Topic
|
|
Grant
|
Determining the role of CUX1 in myeloid neoplasia
|
|
Academic Article
|
Haploinsufficient Transcription Factors in Myeloid Neoplasms.
|